Hypobaric hypoxia as a tool to study pregnancy-dependent responses at the maternal-fetal interface.
نویسندگان
چکیده
Establishment of proper oxygen and nutrient supply to the fetus is essential for a successful pregnancy. The maternal-fetal interface is the site of vascular modifications, providing a conduit for the delivery of essential nutrients to the developing fetus. Pregnancy-dependent adaptive vascular responses within the uteroplacental compartment can be exaggerated by exposure to a physiological stressor such as hypoxia. A simple procedure for exposing pregnant rats and mice to hypobaric hypoxia is presented.
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ورودعنوان ژورنال:
- Methods in molecular medicine
دوره 122 شماره
صفحات -
تاریخ انتشار 2006